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Monellin

  1. Precision Fermentation
  2. Proteins
  3. Sweet
  4. Monellin

    Technical Data

    Type of Protein Sweet
    Protein name Monellin
    Companies producing this protein
    • Oobli
    • 21st.Bio
    Function (dairy alternative, colorant, texture, taste...) Sweet taste (Saraiva et al., 2023)
    Target application (cheese, infant formula, meat...) Could be used as a sweetener, but the native form of monellin is not commercially used because of its low stability. The protein could be modified to increase its stability (Farag et al., 2022).
    Purity requirement/purification values
    • Has been isolated at 95% purity at large scale (I. H. Kim & Lim, 1996)
    • >50% pure in the application of Oobli
    Techno-functional properties Not very thermostable (Asr et al., 2022)
    Nutritional properties Low-calorie (Farag et al., 2022)
    Advantages Tested on animal models and concluded to be safe, showed no allergenic, cytoogenic or mutagenic properties (Novik et al., 2023)
    Challenges/risk factors
    • Thermolable: denatures at temperatures above 50°C and loses its sweetness completely (Asr et al., 2022).
    • Delayed sweetness and licorice-like taste (Zeece, 2020)
    • Loses its sweetness in carbonated drinks such as cola (Farag et al., 2022)
    Komagatella phaffi (Pichia pastoris)

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